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A similarly high serum DMD-CH MICA concentration, in a subject not displaying any toxicity symptoms, has been reported once before . This may result from tolerance building after chronic use of SC. The zebra fish system produced a similar result with 16 of the same 17 metabolites identified. The present cases represent only a small part of the Poisons Information Center calls on SC presented in Fig. Zebra fish.
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The analysis of synthetic cannabis compounds in a urine sample is currently one of the more complex tasks facing toxicologists. The list of prevalent compounds in circulation at any given time is constantly in flux, changing at a rapid rate to avoid legal control and to a lesser extent to avoid detection. With proper knowledge of the correct analytical targets, relatively simple procedures are capable of extracting and analyzing synthetic cannabis.
Metabolite of the M2 Group (Hydrogenation at Indolent)
The fragmentation of M2.2 included the elimination of the glucagon acid moiety (M2.1).This fragmentation pathway exhibits carbonation of a butane moiety.
Metabolite of the M3 Group (Ester Hydrolysis and Elucidation)
The elucidated metabolite M3.2 underwent a significant in-source fragmentation, forming the detonated M3.1 molecule which is common to glucagon esters.